Physicochemical Interactions of Metformin Hydrochloride and Glibenclamide with Several Health Foods
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چکیده
منابع مشابه
Physicochemical interactions of metformin hydrochloride and glibenclamide with several health foods.
In this study, as an approach to possible pharmacokinetic interactions between antidiabetic agents and health foods, we investigated the binding of metformin and glibenclamide to aojiru, kurosu, and blueberry extract using a dialysis method. The permeation of metformin from the inner to the outer side of the dialysis tube during 90 min was not altered in the presence of aojiru or kurosu, and sl...
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Metformin hydrochloride, a drug group of biguanides, with significant efficacy in the treatment of diabetes type II, is decomposed before reaching to the stomach and is wasted in great losses. In this study, the nanoliposomes of metformin hydrochloride were prepared with Bingham method. At first, the single factor test is done. Design variables are: lecithin to cholesterol ratio, organic solven...
متن کاملSynthesis of Metformin Hydrochloride nanoliposomes: Evaluation of physicochemical characteristics and release kinetics
Metformin hydrochloride, a drug group of biguanides, with significant efficacy in the treatment of diabetes type II, is decomposed before reaching to the stomach and is wasted in great losses. In this study, the nanoliposomes of metformin hydrochloride were prepared with Bingham method. At first, the single factor test is done. Design variables are: lecithin to cholesterol ratio, organic solven...
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متن کاملSimultaneous spectrophotometric determination of metformin hydrochloride and glibenclamide in binary mixtures using combined discrete and continuous wavelet transforms.
In this work, a combined discrete and continuous wavelet transform analysis was developed for simultaneous spectrophotometric determinations of metformin hydrochloride and glibenclamide, two antidiabetic drugs, in binary mixtures without any chemical pretreatment. Absorption spectra were subjected to the 4-level db4 discrete wavelet transform (DWT) for signal de-noising. Selected continuous wav...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2008
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.128.1341